Vitamin B1 Against Kidney Damage in Diabetics
Filed in archive Research on December 9, 2008
Diabetics are prone to kidney damage also called diabetic nephropathy. However, albumin excretion rates determine the extent of the kidney disease.
Microalbuminuria occurs when small amounts of albumin - the most abundant protein in human serum - leaks from the kidney into the urine. It is a marker of early kidney disease development in diabetics.
Now it has been found that daily high doses of Vitamin B1 (thiamine) for three months reduced the rate of albumin excretion in type 2 diabetics by 41 per cent.
The albumin excretion rate was decreased by 41% from the value at the start of the study. The results also showed 35% of patients with microalbuminuria saw a return to normal urinary albumin excretion after being treated with thiamine.
"In this pilot study, high-dose thiamine therapy produced a regression of urinary albumin excretion (UAE) in type-2 diabetic patients with microalbuminuria," wrote the researchers in the journal Diabetologia.
"Thiamine supplements at high dose may provide improved therapy for early-stage diabetic nephropathy."
The said study was from England and Pakistan. Read more from NutraIngredients.
"In this pilot study, high-dose thiamine therapy produced a regression of urinary albumin excretion (UAE) in type-2 diabetic patients with microalbuminuria," wrote the researchers in the journal Diabetologia.
"Thiamine supplements at high dose may provide improved therapy for early-stage diabetic nephropathy."
Tags: albumin excretion Vitamin B Thiamine kidney disease diabetics diabetes albumin+excretion
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