Once-weekly Exenatide Long-acting Release (LAR) Injection Found Superior Over Twice-Daily BYETTA® (exenatide) Injection
Filed in archive Developments , News , Treatment on November 6, 2007
Positive results of a comparator study of once-weekly exenatide long-acting release (LAR) injection and byetta® (exenatide) injection taken twice daily in patients with type 2 diabetes have recently been announced by Amylin Pharmaceuticals, Inc., Eli Lilly and Company and Alkermes, Inc..
Once-weekly exenatide, an investigational drug, showed a statistically significant improvement in A1C of approximately 1.9 percentage points from baseline, compared to an improvement of approximately 1.5 percentage points for BYETTA®.
Approximately three out of four subjects treated with once-weekly exenatide achieved an A1C of 7 percent or less. A1C of less than 7 percent is the target for good glucose control as recommended by the American Diabetes Association.
Indicated for use twice a day in adults with type 2 diabetes who are unsuccessful at controlling their blood sugar levels using common oral diabetes medications - BYETTA® - is the first and only FDA-approved incretin mimetic approved in April 2005 by the FDA.

Now, the once-weekly exenatide long-acting release (LAR) injection is still in the pipeline which Amylin (and its collaborators) expect to file for FDA approval in mid-2009.
While we have heard so many positive feedback from those using BYETTA®, now it is even getting better with the new version.
Find more details from the Amylin Pharma press release.
[Photo Credit: NY Times]
Approximately three out of four subjects treated with once-weekly exenatide achieved an A1C of 7 percent or less. A1C of less than 7 percent is the target for good glucose control as recommended by the American Diabetes Association.
Tags: onceweekly exenatide longacting release LAR injection BYETTA® exenatide injection type 2 diabetes 5
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