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Fenofibrate and Risk of Amputation in Diabetes

Filed in archive Research , Treatment on May 25, 2009

Fenofibrate and Risk of Amputation in Diabetes
The cholesterol-lowering drug fenofibrate, when used in the treatment of type 2 diabetes cuts the risk of a first diabetes-related limb amputation by 36%.

Such were the findings recently reported in The Lancet.

From WebMD:

"I would call that a substantial reduction in risk," says James Best, MD, professor of medicine at the University of Melbourne in Australia and a co-author of the study.

The reduction in limb amputation risk is probably not directly related to the cholesterol-lowering effects of the drug, he tells WebMD, but rather to some of the other effects, such as improving the functioning of small blood vessels.


The functions of the small blood vessels are improved by fenofibrate thereby reducing the risk of amputation in people with diabetes.


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Tags: fenofibrate  small  blood  vessels  amputation  diabetes  risk  amputation+diabetes 

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